• Chitosan in Mucoadhesive Drug Delivery: Focus on Local Vaginal Therapy 

      Andersen, Toril; Bleher, Stefan; Flaten, Gøril Eide; Tho, Ingunn; Mattsson, Sofia; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-01-07)
      Mucoadhesive drug therapy destined for localized drug treatment is gaining increasing importance in today’s drug development. Chitosan, due to its known biodegradability, bioadhesiveness and excellent safety profile offers means to improve mucosal drug therapy. We have used chitosan as mucoadhesive polymer to develop liposomes able to ensure prolonged residence time at vaginal site. Two types of ...